BP-EVs: A Novel Source of EVs in the Nanocarrier Field

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dc.contributor.authorLorca, Cristina
dc.contributor.authorFernández-Rhodes, María
dc.contributor.authorSánchez Milán, José Antonio
dc.contributor.authorMulet, Maria
dc.contributor.authorLisa, Julia
dc.contributor.authorGallart Palau, Xavier Ramon
dc.contributor.authorSerra, Aida
dc.date.accessioned2024-05-24T09:15:38Z
dc.date.available2024-05-24T09:15:38Z
dc.date.issued2023
dc.description.abstractExtracellular vesicles (EVs) represent a complex mechanism of molecular exchange that has garnered significant attention in recent times. Nonetheless, identifying sustainable sources of biologically safe EVs remains challenging. This chapter delves into the utilization of fermented food industry by-products as a circular and secure reservoir of biocompatible EVs, dubbed as BP-EVs. BP-EVs demonstrate excellent oral bioavailability and biodistribution, with negligible cytotoxicity, and a preferential targeting capacity toward the central nervous system, liver, and skeletal tissues. The ease of editing BP-EVs is also depicted using the most common EV editing methods in this chapter. Globally, these groundbreaking findings are poised to unlock significant avenues for leveraging BP-EVs as an optimal source of biocompatible nanovesicles across a wide array of applications within the bioeconomy and biomedical fields. These applications primarily target molecule delivery into the central nervous system and skeletal tissue but are not limited to these two organism systems.
dc.format.extent19 p.
dc.identifier.doihttps://doi.org/10.5772/intechopen.113891
dc.identifier.isbn978-0-85014-031-6
dc.identifier.isbn978-0-85014-030-9
dc.identifier.urihttps://hdl.handle.net/10459.1/465791
dc.language.isoeng
dc.publisherIntechOpen
dc.relation.ispartofExtracellular Vesicles - Applications and Therapeutic Potential Edited by Manash K. Paul
dc.rightscc-by (c) The Authors, 2023
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0*
dc.subjectExtracellular vesicles
dc.subjectCircular economy
dc.subjectNanocarriers
dc.subjectUpcycling
dc.subjectCompound delivery
dc.titleBP-EVs: A Novel Source of EVs in the Nanocarrier Field
dc.typeinfo:eu-repo/semantics/bookPart
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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