Recent Submissions

  • Factors influencing intention to participate in breast cancer screening. An exploratory structural model 

    López-Panisello, María Belén; Pérez Lacasta, María José; Rué i Monné, Montserrat; Carles Lavila, Misericordia (Public Library of Science, 2023-02-03)
    Objectives The paper has two objectives. The first one examines whether informing women about the benefits and adverse effects of breast cancer screening could have an effect on three variables: their knowledge, the ...
  • Proteomic profiling for prediction of recurrent cardiovascular event in patients with acute coronary syndrome and obstructive sleep apnea: A post-hoc analysis from the ISAACC study 

    Zapater, Andrea; Gracia-Lavedan, Esther; Torres, Gerard; Minguez Roure, Olga; Pascual, Lydia; Cortijo, Anunciación; Martínez, Dolores; Benítez, Iván; Batlle Garcia, Jordi de; Henríquez Beltrán, Mario; Abad, Jorge; Durán-Cantolla, Joaquín; Urrutia, Amaia; Mediano, Olga; Masdeu, María José; Ordax-Carbajo, Estrella; Masa, Juan Fernando; Peña, Mónica de la; Mayós Pérez, Mercè; Coloma, Ramón; Montserrat, Josep Maria; Chiner, Eusebi; Barbé Illa, Ferran; Sánchez de la Torre, Manuel (Elsevier, 2023)
    Background: Obstructive sleep apnea (OSA) is associated with a recurrent cardiovascular event (CVE) risk in patients with a first acute coronary syndrome (ACS). However, the pathological pathways by which OSA promotes this ...
  • Lymph Node Tumor Burden Correlates With Tumor Budding and Poorly Differentiated Clusters: A New Prognostic Factor in Colorectal Carcinoma? 

    Archilla, Ivan; Diaz-Mercedes, Sherley; Aguirre, José Javier; Tarragona Foradada, Jordi; Machado, Isidro; Rodrigo-Calvo, María Teresa; Lopez-Prades, Sandra; Gorostiaga, Iñigo; Landolfi, Stefania; Otero Alén, Begoña; Balaguer, Francesc; Castells, Antoni; Camps, Jordi; Cuatrecasas, Miriam (Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology, 2021)
    Introduction: Molecular lymph node (LN) staging in early colorectal cancer (CRC) has demonstrated to be more precise than conventional histopathology pN staging. Tumor budding (TB) and poorly differentiated clusters (PDCs) ...
  • Cytology Smears: An enhanced alternative method for colorectal cancer pN Stage-A multicentre study 

    Diaz-Mercedes, Sherley; Archilla, Ivan; Lahoz, Sara; Rodrigo-Calvo, María Teresa; Lopez-Prades, Sandra; Tarragona Foradada, Jordi; Landolfi, Stefania; Concha, Ángel; Machado, Isidro; Maurel, Joan; Chic, Nuria; Castells, Antoni; Balaguer, Francesc; Camps, Jordi; Cuatrecasas, Miriam (MDPI, 2022-12-09)
    Stage II colorectal cancer (CRC) recurrence remains a clinical problem. Some of these patients are true stage III CRC with a pN0 pathology stage. This large prospective multicentre cohort study aimed at evaluating the ...
  • Pulmonologists’ Opinion on the Use of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease Patients in Spain: A Cross-Sectional Survey 

    Miravitlles Fernández, Marc; González-Torralba, Fernando; Represas-Represas, Cristina; Pomares, Xavier; Márquez-Martín, Eduardo; González, Cruz; Amado, Carlos Antonio; Forné Izquierdo, Carles; Alonso, Soledad; Alcázar-Navarrete, Bernardino; Barrecheguren, Miriam; Jurado Mirete, Juan María; Naval, Elsa (Dove Press; Taylor and Francis Group, 2022)
    Introduction: Identifying the variables that guide decision-making in relation to the use of inhaled corticosteroids (ICS) can contribute to the appropriate use of these drugs. The objective of this study was to identify ...
  • Cardiac tamponade as the initial presentation of a T-cell lymphoblastic lymphoma 

    Belokopytova-Chakh, Alena; Ruiz González, Agustín; Vilardell, Felip; Porcel Pérez, José Manuel (Sociedad Gallega de Medicina Interna, 2022)
    We report a 27-year-old man who presented with cardiac tamponade and was eventually diagnosed of T-cell lymphoblastic lymphoma (T-LBL) by the flow cytometric analysis of pericardial fluid. Despite pericardiocentesis and ...
  • Post-Translational Modifications of PCNA: Guiding for the Best DNA Damage Tolerance Choice 

    Bellí i Martínez, Gemma; Colomina i Gabarrella, Neus; Castells i Roca, Laia; Pérez Lorite, Neus (MDPI, 2022)
    The sliding clamp PCNA is a multifunctional homotrimer mainly linked to DNA replication. During this process, cells must ensure an accurate and complete genome replication when constantly challenged by the presence of DNA ...
  • Evolution of an Iron-Detoxifying Protein: Eukaryotic and Rickettsia Frataxins Contain a Conserved Site Which Is Not Present in Their Bacterial Homologues 

    Alves, Rui; Pazos Gil, Maria; Medina Carbonero, Marta; Sanz Alcázar, Arabela; Delaspre, Fabien; Tamarit Sumalla, Jordi (MDPI, 2022)
    Friedreich’s ataxia is a neurodegenerative disease caused by mutations in the frataxin gene. Frataxin homologues, including bacterial CyaY proteins, can be found in most species and play a fundamental role in mitochondrial ...
  • Blood-based lipidomic signature of severe obstructive sleep apnoea in Alzheimer's disease 

    Dakterzada, Farida; Benítez, Iván; Targa, Adriano; Carnes, Anna; Pujol, Montserrat; Minguez Roure, Olga; Vaca, Rafaela; Sánchez de la Torre, Manuel; Barbé Illa, Ferran; Pamplona Gras, Reinald; Piñol Ripoll, Gerard (BCM, 2022)
    Background: Obstructive sleep apnoea (OSA) is the most frequent form of sleep-disordered breathing in patients with Alzheimer’s disease (AD). Available evidence demonstrates that both conditions are independently associated ...
  • Factor structure of the Maslach Burnout Inventory Human Services Survey in Spanish urgency healthcare personnel: a cross-sectional study 

    Forné Izquierdo, Carles; Yuguero Torres, Oriol (Springer Nature, 2022)
    Background: The Maslach Burnout Inventory (MBI) is an instrument commonly used to evaluate burnout syndrome. The goal of the present study was to assess the internal reliability and the performance of the items and the ...
  • A mathematical model for strigolactone biosynthesis in plants 

    Lucido, Abel; Basallo, Oriol; Sorribas Tello, Albert; Marin-Sanguino, Alberto; Vilaprinyo Terré, Ester; Alves, Rui (Frontiers Media, 2022)
    Strigolactones mediate plant development, trigger symbiosis with arbuscular mycorrhizal fungi, are abundant in 80% of the plant kingdom and help plants gain resistance to environmental stressors. They also induce ...
  • Genome-wide transcriptional profiling of pulmonary functional sequelae in ARDS- secondary to SARS-CoV-2 infection 

    García Hidalgo, María Coronada; Peláez, Rafael; González, Jessica; Santisteve, Sally; Benítez, Iván; Molinero, Marta; Perez-Pons, Manel; Belmonte, Thalía; Torres, Gerard; Moncusí Moix, Anna; Gort Paniello, Clara; Aguilà, Maria; Seck, Faty; Carmona, Paola; Caballero, Jesús; Barberà, Carme; Ceccato, Adrián; Fernández Barat, Laia; Ferrer, Ricard; Garcia-Gasulla, Dario; Lorente, José Ángel; Menéndez, Rosario; Motos, Anna; Peñuelas, Oscar; Riera, Jordi; Bermejo Martin, Jesús F.; Torres, Antoni; Barbé Illa, Ferran; de Gonzalo Calvo, David; Larrayoz, Ignacio M. (Elsevier, 2022)
    Background: Up to 80% of patients surviving acute respiratory distress syndrome (ARDS) secondary to SARS-CoV- 2 infection present persistent anomalies in pulmonary function after hospital discharge. There is a limited ...
  • Ocular Surface plasmacytoma 

    Domínguez Bernaus, Marta; Cid-Bertomeu, Pau; Vilardell, Felip; Huerva, Valentín (European Society of Medicine., 2022)
    Conjunctival plasmacytomas are rare tumours that may be solitary or related with multiple myeloma (MM), a malignant systemic plasma cell neoplasm that tends to metastasize. Plasma cell infiltration of bone ...
  • The ERK5/NF‑κB signaling pathway targets endometrial cancer proliferation and survival 

    Diéguez‑Martínez, Nora; Espinosa‑Gil, Sergio; Yoldi, Guillermo; Gorgisen, Gokhan; Domingo Ortí, Inés; Viñas Casas, Maria; Bolinaga Ayala, Idoia; Megías Roda, Elisabet; Pérez‑Montoyo, Héctor; José Ramón, Bayascas Ramírez; Colás, Eva; Dolcet Roca, Xavier; Lizcano, José M. (Springer Science, 2022)
    Endometrial cancer (EC) is the most common type of gynecologic cancer in women of developed countries. Despite surgery combined with chemo-/radiotherapy regimens, overall survival of patients with high-risk EC tumors is ...
  • Feasibility and Acceptability of Personalized Breast Cancer Screening (DECIDO Study): A Single-Arm Proof-of-Concept Trial 

    Laza-Vásquez, Celmira; Martínez Alonso, Montserrat; Forné Izquierdo, Carles; Vilaplana Mayoral, Jordi; Cruz Esteve, María Inés; Sánchez-López, Isabel; Reñé Reñé, Mercè; Cazorla, Cristina; Hernández Andreu, Marta; Galindo Ortego, Gisela; Llorens Gabandé, Montserrat; Pons Rodríguez, Anna; Rué i Monné, Montserrat; DECIDO Group (MDPI, 2022-08)
    The aim of this study was to assess the acceptability and feasibility of offering risk-based breast cancer screening and its integration into regular clinical practice. A single-arm proof-of-concept trial was conducted ...
  • ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma 

    Concin, Nicole; Matias-Guiu, Xavier; Vergote, Ignace; Cibula, David; Raza Mirza, Mansoor; Marnitz, Simone; Ledermann, Jonathan; Bosse, Tjalling; Chargari, Cyrus; Fagotti, Anna; Fotopoulou, Christina; Gonzalez Martin, Antonio; Lax, Sigurd; Lorusso, Domenica; Marth, Christian; Morice, Philippe; Nout, Remi; O'Donnell, Dearbhaile; Querleu, Denis; Raspollini, Maria Rosaria; Sehouli, Jalid; Sturdza, Alina; Taylor, Alexandra; Westermann, Anneke; Wimberger, Pauline; Colombo, Nicoletta; Planchamp, François; Creutzberg, Carien (BMJ, 2021)
    A European consensus conference on endometrial carcinoma was held in 2014 to produce multi-disciplinary evidence-based guidelines on selected questions. Given the large body of literature on the management of endometrial ...
  • Bulk autophagy induction and life extension is achieved when iron is the only limited nutrient in Saccharomyces cerevisiae 

    Montellá-Manuel, Sandra; Pujol Carrión, Núria; Mechoud, Mónica A.; Torre Ruiz, M. A. de la (Portland Press; Biochemical Society, 2021)
    We have investigated the effects that iron limitation provokes in Saccharomyces cerevisiae exponential cultures. We have demonstrated that one primary response is the induction of bulk autophagy mediated by TORC1. Coherently, ...
  • A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes 

    Altés, Gisela; Vaquero, Marta; Cuesta, Sara; Anerillas Aljama, Carlos; Macià Armengol, Anna; Espinet Mestre, Carme; Ribera i Calvet, Joan; Bellusci, Saverio; Klein, Ophir D.; Yeramian Hakim, Andree; Dolcet Roca, Xavier; Egea Navarro, Joaquim; Encinas Martín, Mario (Springer, 2022)
    The Wolffian ducts (WD) are paired epithelial tubules central to the development of the mammalian genitourinary tract. Outgrowths from the WD known as the ureteric buds (UB) generate the collecting ducts of the kidney. ...
  • Identification of NHLRC1 as a Novel AKT Activator from a Lung Cancer Epigenome-Wide Association Study (EWAS) 

    Faltus, Christian; Lahnsteiner, Angelika; Barrdahl, Myrto; Assenov, Yassen; Hüsing, Anika; Bogatyrova, Olga; Laplana Lafaja, Marina; Johnson, Theron; Muley, Thomas; Meister, Michael; Warth, Arne; Thomas, Michael; Plass, Christoph; Kaaks, Rudolf; Risch, Angela (MDPI, 2022)
    Changes in DNA methylation identified by epigenome-wide association studies (EWAS) have been recently linked to increased lung cancer risk. However, the cellular effects of these differentially methylated positions (DMPs) ...
  • Metabolic engineering of Halomonas elongata: Ectoine secretion is increased by demand and supply driven approaches 

    Hobmeier, Karina; Oppermann, Martin; Stasinski, Natalie; Kremling, Andreas; Pflüger Grau, Katharina; Kunte, Hans Jörg; Marin-Sanguino, Alberto (Frontiers Media, 2022)
    The application of naturally-derived biomolecules in everyday products, replacing conventional synthetic manufacturing, is an ever-increasing market. An example of this is the compatible solute ectoine, which is contained ...

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